Alcohol Dehydrogenase 1C (ADH1C) Reagents

Alcohol dehydrogenase 1C

Cytoplasm.

Zinc-containing alcohol dehydrogenase family

Signal Transduction

ADH gamma subunit; ADH1C; ADH1G_HUMAN; Adh3; Alcohol dehydrogenase 1C (class I) gamma polypeptide; Alcohol dehydrogenase 1C; Alcohol dehydrogenase 1C gamma polypeptide; Alcohol dehydrogenase 3 (class I) gamma polypeptide; Alcohol dehydrogenase 3; Alcohol dehydrogenase subunit gamma; Aldehyde reductase; Class I alcohol dehydrogenase; OTTHUMP00000220209

This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation to acetaldehyde, thus playing a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. An association between ADH1C polymorphism and alcohol dependence has not been established.