Ap-3 Complex Subunit Beta-2 (AP3B2) Reagents

AP-3 complex subunit beta-2

Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals

Epileptic encephalopathy, early infantile, 48 (EIEE48)

Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus.

Adaptor complexes large subunit family

Isoform 1 expression is specific to nervous system. Expressed in nerve terminal and cell body, and is associated with nerve-terminal vesicles. Expression seen in Purkinje cells, cortical neurons, neuroectodermal tumors and graded in cerebral cortex (deepe

Neuroscience

Adapter-related protein complex 3 subunit beta-2; Adaptor protein complex AP-3 subunit beta-2; Adaptor related protein complex 3 beta 2 subunit; AP 3 complex subunit beta 2; AP-3 complex subunit beta-2; AP3B2; AP3B2_HUMAN; beta NAP; Beta-3B-adaptin; Beta3B adaptin; Beta3b; Clathrin assembly protein complex 3 beta 2 large chain; Clathrin assembly protein complex 3 beta-2 large chain; NAPTB; Neuron specific vesicle coat protein and cerebellar degeneration antigen; Neuron-specific vesicle coat protein beta-NAP; Neuronal adaptin like protein beta subunit