Leucine-Rich Repeat-Containing Protein 59 (LRRC59) Reagents

Leucine-rich repeat-containing protein 59

Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores.

Microsome membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein. Nucleus envelope. Note=Localization in the nuclear envelope depends upon the nuclear import machinery, including KPNB1.

Widely expressed.

Leucine rich repeat containing 59; Leucine-rich repeat-containing protein 59; LRC59_HUMAN; LRRC59; p34; PRO1855; Ribosome binding protein p34

Enables RNA binding activity and cadherin binding activity. Predicted to be involved in positive regulation of Ras protein signal transduction and signal transduction. Located in endoplasmic reticulum and mitochondrial nucleoid.