Amino acids 40-493 form the expressed segment for recombinant Human MLYCD. The calculated molecular weight for this MLYCD protein is 55.9 kDa. This MLYCD protein is produced using e.coli expression system. The MLYCD gene fragment has been modified by fusing the N-terminal 10xHis tag and C-terminal Myc tag, providing convenience in detecting and purifying the recombinant MLYCD protein during the following stages.Human malonyl-CoA decarboxylase (MLYCD) is a mitochondrial enzyme that catalyzes the conversion of malonyl-CoA to acetyl-CoA and carbon dioxide, playing a crucial role in fatty acid metabolism. By reducing malonyl-CoA levels, MLYCD alleviates its inhibitory effect on carnitine palmitoyltransferase 1 (CPT1), thus promoting fatty acid oxidation and mitochondrial energy production. MLYCD deficiency leads to the accumulation of malonyl-CoA, impairing fatty acid oxidation and causing symptoms such as cardiomyopathy, skeletal myopathy, and developmental delay. Research on MLYCD spans various areas, including lipid metabolism, mitochondrial function, and metabolic disorders, aiming to elucidate its role in health and disease and develop potential therapeutic strategies.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[20834],"class_list":["post-109757","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-mlycd","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n