The fusion tag N-terminal 6xHis-B2M tag gene was added to the gene sequence corresponding to the E.coli of the human YAP1 protein to form the recombinant DNA. The recombinant DNA was cloned into the expression vector and then transformed into the E.coli for expression. Following purification, the product is the recombinant human YAP1 protein carrying N-terminal 6xHis-B2M tag. The SDS-PAGE assessed the purity of this recombinant YAP1 protein up to 85%. It had an apparent molecular weight of approximately 78 kDa. This recombinant YAP1 protein may be used in YAP1-mediated cancer research.YAP1 is a gene encoding a protein named transcriptional coactivator YAP1 (abbreviated YAP1) in human and belongs to YAP1 family. This protein acts as a transcriptional regulator by activating the transcription of genes involved in cell proliferation and suppressing apoptotic genes. It is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. Reported diseases associated with YAP1 include Coloboma, Ocular, With Or Without Hearing Impairment, Cleft Lip\/Palate, And\/Or Mental Retardation and Coloboma Of Macula.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[347],"class_list":["post-110432","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-yap1","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n