Amino acids 1-428 constitute the expression domain of recombinant Human HDAC3. This HDAC3 protein is expected to have a theoretical molecular weight of 64.8 kDa. Expression of this HDAC3 protein is conducted in e.coli. The HDAC3 gene fragment has been modified by fusing the N-terminal 6xHis-SUMO tag, providing convenience in detecting and purifying the recombinant HDAC3 protein during the following stages.Histone deacetylase 3 (HDAC3) is a crucial enzyme involved in epigenetic regulation by catalyzing the removal of acetyl groups from histone proteins. As part of the histone deacetylase family, HDAC3 plays a key role in controlling gene expression and chromatin structure. It is essential for various cellular processes, including cell cycle progression, differentiation, and apoptosis. HDAC3 is often found in multi-protein complexes and is implicated in the regulation of diverse biological pathways. Dysregulation of HDAC3 has been associated with several diseases, including cancer and neurological disorders. Targeting HDAC3 has become a focus in drug development for potential therapeutic interventions, making it a subject of interest in both basic research and clinical studies.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[39108],"class_list":["post-111355","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-hdac3","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n