Connector Enhancer Of Kinase Suppressor Of Ras 2 (CNKSR2) Reagents

Connector enhancer of kinase suppressor of ras 2

May function as an adapter protein or regulator of Ras signaling pathways.

Cytoplasm. Membrane; Peripheral membrane protein.

CNKSR family

Signal Transduction

CNKSR2; CNK2; KIAA0902; KSR2Connector enhancer of kinase suppressor of ras 2; Connector enhancer of KSR 2; CNK homolog protein 2; CNK2

This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene.