Large Ribosomal Subunit Protein Bl36M (MRPL36) Reagents

Large ribosomal subunit protein bL36m

Mitochondrion.

Bacterial ribosomal protein bL36 family

39S ribosomal protein L36; 39S ribosomal protein L36 mitochondrial; BRCA1-interacting protein 1; BRIP1; L36mt; mitochondrial; Mitochondrial ribosomal protein L36; MRP L36; MRP-L36; Mrpl36; PRPL36; Putative BRCA1 interacting protein; RM36_HUMAN; RPMJ

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 2p.