Ring Finger Protein Unkempt Homolog (UNK) Reagents

RING finger protein unkempt homolog

Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during embryonic development. Acts as a translation repressor and controls a translationally regulated cell morphology program to ensure proper structuring of the nervous system. Translational control depends on recognition of its binding element within target mRNAs which consists of a mandatory UAG trimer upstream of a U/A-rich motif. Associated with polysomes.

Cytoplasm.

Unkempt family

KIAA1753; RING finger protein unkempt homolog; Unk; UNK_HUMAN; ZC3H5; ZC3HDC5; Zinc finger CCCH domain-containing protein 5