{"id":108474,"date":"2025-12-25T12:46:24","date_gmt":"2025-12-25T12:46:24","guid":{"rendered":"https:\/\/advbiomart.sytech.site\/product\/recombinant-human-guanine-nucleotide-binding-protein-g-i-subunit-alpha-1-gnai1-acp01072\/"},"modified":"2025-12-25T12:46:25","modified_gmt":"2025-12-25T12:46:25","slug":"recombinant-human-guanine-nucleotide-binding-protein-g-i-subunit-alpha-1-gnai1-acp01072","status":"publish","type":"product","link":"https:\/\/www.abtriva.com\/de\/product\/recombinant-human-guanine-nucleotide-binding-protein-g-i-subunit-alpha-1-gnai1-acp01072\/","title":{"rendered":"Recombinant Human Guanine nucleotide-binding protein G (i) subunit alpha-1 (GNAI1)"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"<p>The expression region of this recombinant Human GNAI1 covers amino acids 2-354. This GNAI1 protein is expected to have a theoretical molecular weight of 47.7 kDa. This GNAI1 recombinant protein is manufactured in e.coli. The GNAI1 coding gene included the N-terminal 10xHis tag and C-terminal Myc tag, which simplifies the detection and purification processes of the recombinant GNAI1 protein in following stages of expression and purification.The human guanine nucleotide-binding protein G (i) subunit alpha-1 (GNAI1) is a member of the G-alpha subunit family, which plays a pivotal role in transducing signals from G-protein-coupled receptors (GPCRs) to intracellular effectors. GNAI1 inhibits adenylyl cyclase, leading to decreased cyclic AMP (cAMP) production and downstream signaling. This negatively regulates cellular processes such as neurotransmission, hormone secretion, and cell growth. GNAI1 is involved in various physiological functions, including the modulation of cardiovascular responses, neuronal activity, and immune cell function. Dysregulation of GNAI1 has been associated with several diseases, emphasizing its importance as a signaling molecule and a potential therapeutic target in various disorders.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[74581],"class_list":["post-108474","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-gnai1","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Recombinant Human Guanine nucleotide-binding protein G (i) subunit alpha-1 (GNAI1) - AbTrivia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.abtriva.com\/de\/product\/recombinant-human-guanine-nucleotide-binding-protein-g-i-subunit-alpha-1-gnai1-acp01072\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Recombinant Human Guanine nucleotide-binding protein G (i) subunit alpha-1 (GNAI1) - AbTrivia\" \/>\n<meta property=\"og:description\" content=\"The expression region of this recombinant Human GNAI1 covers amino acids 2-354. This GNAI1 protein is expected to have a theoretical molecular weight of 47.7 kDa. This GNAI1 recombinant protein is manufactured in e.coli. The GNAI1 coding gene included the N-terminal 10xHis tag and C-terminal Myc tag, which simplifies the detection and purification processes of the recombinant GNAI1 protein in following stages of expression and purification.The human guanine nucleotide-binding protein G (i) subunit alpha-1 (GNAI1) is a member of the G-alpha subunit family, which plays a pivotal role in transducing signals from G-protein-coupled receptors (GPCRs) to intracellular effectors. GNAI1 inhibits adenylyl cyclase, leading to decreased cyclic AMP (cAMP) production and downstream signaling. This negatively regulates cellular processes such as neurotransmission, hormone secretion, and cell growth. GNAI1 is involved in various physiological functions, including the modulation of cardiovascular responses, neuronal activity, and immune cell function. Dysregulation of GNAI1 has been associated with several diseases, emphasizing its importance as a signaling molecule and a potential therapeutic target in various disorders.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.abtriva.com\/de\/product\/recombinant-human-guanine-nucleotide-binding-protein-g-i-subunit-alpha-1-gnai1-acp01072\/\" \/>\n<meta property=\"og:site_name\" content=\"AbTrivia\" \/>\n<meta property=\"article:modified_time\" content=\"2025-12-25T12:46:25+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.abtriva.com\/de\/product\/recombinant-human-guanine-nucleotide-binding-protein-g-i-subunit-alpha-1-gnai1-acp01072\/\",\"url\":\"https:\/\/www.abtriva.com\/de\/product\/recombinant-human-guanine-nucleotide-binding-protein-g-i-subunit-alpha-1-gnai1-acp01072\/\",\"name\":\"Recombinant Human Guanine nucleotide-binding protein G (i) subunit alpha-1 (GNAI1) - AbTrivia\",\"isPartOf\":{\"@id\":\"https:\/\/abtriva.com\/cn\/#website\"},\"datePublished\":\"2025-12-25T12:46:24+00:00\",\"dateModified\":\"2025-12-25T12:46:25+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.abtriva.com\/de\/product\/recombinant-human-guanine-nucleotide-binding-protein-g-i-subunit-alpha-1-gnai1-acp01072\/#breadcrumb\"},\"inLanguage\":\"de_DE\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.abtriva.com\/de\/product\/recombinant-human-guanine-nucleotide-binding-protein-g-i-subunit-alpha-1-gnai1-acp01072\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.abtriva.com\/de\/product\/recombinant-human-guanine-nucleotide-binding-protein-g-i-subunit-alpha-1-gnai1-acp01072\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.abtriva.com\/de\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Products\",\"item\":\"https:\/\/www.abtriva.com\/de\/shop\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Proteins\",\"item\":\"https:\/\/www.abtriva.com\/de\/category\/proteins\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Recombinant Proteins\",\"item\":\"https:\/\/www.abtriva.com\/de\/category\/proteins\/recombinant-proteins\/\"},{\"@type\":\"ListItem\",\"position\":5,\"name\":\"Recombinant Human Guanine nucleotide-binding protein G (i) subunit alpha-1 (GNAI1)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/abtriva.com\/cn\/#website\",\"url\":\"https:\/\/abtriva.com\/cn\/\",\"name\":\"AbTrivia\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/abtriva.com\/cn\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"de_DE\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Recombinant Human Guanine nucleotide-binding protein G (i) subunit alpha-1 (GNAI1) - AbTrivia","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.abtriva.com\/de\/product\/recombinant-human-guanine-nucleotide-binding-protein-g-i-subunit-alpha-1-gnai1-acp01072\/","og_locale":"de_DE","og_type":"article","og_title":"Recombinant Human Guanine nucleotide-binding protein G (i) subunit alpha-1 (GNAI1) - AbTrivia","og_description":"The expression region of this recombinant Human GNAI1 covers amino acids 2-354. 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