The expression region of this recombinant Human SLC5A5 covers amino acids 547-643. The calculated molecular weight for this SLC5A5 protein is 17.4 kDa. This SLC5A5 protein is produced using e.coli expression system. The SLC5A5 coding gene included the C-terminal 6xHis tag, which simplifies the detection and purification processes of the recombinant SLC5A5 protein in following stages of expression and purification.The human sodium\/iodide cotransporter (SLC5A5) is a crucial membrane protein involved in the active transport of iodide ions across the cell membrane. Mainly expressed in thyroid follicular cells, SLC5A5 plays a pivotal role in thyroid hormone synthesis. It facilitates the uptake of iodide from the bloodstream into thyroid cells, an essential step for the production of thyroid hormones, thyroxine (T4), and triiodothyronine (T3). This process is integral to the regulation of metabolism and overall physiological homeostasis. Additionally, due to its ability to concentrate iodide, SLC5A5 has been utilized in medical imaging and radioiodine therapy for thyroid disorders, including thyroid cancer.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[6471],"class_list":["post-108572","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-slc5a5","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n