The expression region of this recombinant Human KYNU covers amino acids 1-307. This KYNU protein is expected to have a theoretical molecular weight of 61.6 kDa. This protein is generated in a e.coli-based system. Fusion of the N-terminal GST tag into the KYNU encoding gene fragment was conducted, allowing for easier detection and purification of the KYNU protein in subsequent stages.human kynureninase (KYNU) is a crucial enzyme in the tryptophan catabolic pathway, catalyzing the conversion of kynurenine to anthranilic acid. KYNU plays a pivotal role in regulating the levels of neuroactive kynurenine metabolites, influencing neurotransmission and immune responses. In neurobiology, KYNU is implicated in neurodegenerative diseases and psychiatric disorders due to its involvement in kynurenine metabolism. In immunology research, KYNU modulates immune tolerance and inflammation. Furthermore, KYNU’s role in cancer metabolism underscores its significance in oncology. Investigating KYNU provides insights into tryptophan metabolism, offering potential applications in neurology, immunology, and cancer research, with implications for therapeutic strategies targeting these pathways.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[21945],"class_list":["post-109499","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-kynu","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n