The recombinant Human CYP11B2 was expressed with the amino acid range of 25-503. The calculated molecular weight for this CYP11B2 protein is 71 kDa. This CYP11B2 protein is produced using e.coli expression system. The CYP11B2 gene fragment has been modified by fusing the N-terminal 6xHis-SUMO tag, providing convenience in detecting and purifying the recombinant CYP11B2 protein during the following stages.Human cytochrome P450 11B2 (CYP11B2) is a mitochondrial enzyme crucial for aldosterone biosynthesis in the adrenal glands. CYP11B2 catalyzes the final steps in the synthesis of aldosterone, a mineralocorticoid hormone that regulates electrolyte and fluid balance by acting on the kidneys. Aldosterone, in turn, plays a key role in maintaining blood pressure and electrolyte homeostasis by promoting sodium retention and potassium excretion in the kidneys. Dysfunction of CYP11B2 can lead to disorders such as hyperaldosteronism, impacting blood pressure regulation. Research on CYP11B2 contributes to understanding adrenal steroidogenesis and potential therapeutic targets for related conditions.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[17851],"class_list":["post-109700","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-cyp11b2","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n