The expression region of this recombinant Human CA9 covers amino acids 64-399. The theoretical molecular weight of the CA9 protein is 66.8 kDa. This protein is generated in a e.coli-based system. Fusion of the N-terminal 6xHis-GST tag into the CA9 encoding gene fragment was conducted, allowing for easier detection and purification of the CA9 protein in subsequent stages.Human carbonic anhydrase 9 (CA9) is a key enzyme involved in pH regulation and hypoxic adaptation. Primarily expressed in hypoxic tumor environments, CA9 facilitates the conversion of carbon dioxide to bicarbonate ions and protons. In cancer research, CA9 serves as a biomarker for hypoxia and tumor progression, offering diagnostic and prognostic insights. Targeting CA9 in anticancer strategies aims to disrupt pH homeostasis in tumor cells. Furthermore, CA9’s involvement in acid-base balance makes it a subject of interest in nephrology and cardiovascular research.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[337],"class_list":["post-109995","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-ca9","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n