The region for expressing recombinant Human HMGN2 contains amino acids 1-90. The theoretical molecular weight of the HMGN2 protein is 36.4 kDa. The HMGN2 protein was expressed in e.coli. The HMGN2 gene fragment has been modified by fusing the N-terminal GST tag, providing convenience in detecting and purifying the recombinant HMGN2 protein during the following stages.The human non-histone chromosomal protein HMG-17, encoded by the HMGN2 gene, is involved in chromatin structure regulation and plays a role in transcriptional regulation. HMG-17 binds to nucleosomes and alters the structure of chromatin, affecting the accessibility of transcription factors to DNA. HMG-17 is known to influence gene expression, participating in both activation and repression of transcription. Additionally, it has been implicated in various cellular processes, including DNA repair and maintenance of genomic stability. Research on HMGN2 spans multiple areas, such as understanding its precise mechanisms in chromatin dynamics, its impact on gene regulation, and its potential implications in diseases like cancer. Investigations into HMGN2 contribute to unraveling the complex network of chromatin-associated proteins and their roles in cellular function.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[54878],"class_list":["post-110843","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-hmgn2","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n