Amino acids 1-305 constitute the expression domain of recombinant Human RALGPS1. The calculated molecular weight for this RALGPS1 protein is 50.7 kDa. This protein is generated in a e.coli-based system. Fusion of the N-terminal 6xHis-SUMO tag into the RALGPS1 encoding gene fragment was conducted, allowing for easier detection and purification of the RALGPS1 protein in subsequent stages.Human ras-specific guanine nucleotide-releasing factor RALGPS1 is a key regulator of the Ras small GTPases. RALGPS1 activates RalA and RalB, influencing cellular processes like vesicle trafficking, cell migration, and oncogenic transformation. In cancer research, RALGPS1 is implicated in tumor progression and metastasis, making it a potential therapeutic target. In cell biology, RALGPS1 is essential for understanding Ras signaling and intracellular dynamics. Additionally, RALGPS1 plays a role in synaptic transmission and neurodevelopment. Investigating RALGPS1 provides insights into molecular mechanisms of Ras activation, offering potential applications in cancer therapeutics, neurological research, and broader cell signaling studies, enhancing the understanding of cellular processes and diseases.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[69605],"class_list":["post-111322","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-ralgps1","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n