To produce recombinant Human SOX2 protein, a well-established recombinant DNA technology is the key. A DNA template of SOX2 was constructed with N-terminal 6xHis-SUMO tag using the technique. Once the template was made, the recombinant Human SOX2 protein could be produced with it efficiently. CUSABIO has built a strict QC system to ensure quality. The expression region is 1-317aa of the Human SOX2. The purity of this recombinant is 85% determined by SDS-PAGE. SOX2 is a protein coding gene that encodes Transcription factor SOX-2. According to some studies, SOX2 may have the following features.The basic function of Sox2 is to stabilize ES cells in a pluripotent state by maintaining the necessary expression levels of Oct3\/4. Oct4 and Sox2 bind to the Nanog promoter in live mouse and human embryonic stem cells. Pluripotent cell lines in early mouse development depend on SOX2 function. Constitutive expression of SOX2 inhibits neuronal differentiation and leads to the maintenance of primary characteristics. SOX2 controls tumorigenesis and cancer stem cell function in squamous cell carcinoma. SOX2 is an amplified linear survival oncogene in lung and esophageal squamous cell carcinoma.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[48151],"class_list":["post-111501","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-sox2","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n