Rod Outer Segment Membrane Protein 1 (ROM1) Reagents

Rod outer segment membrane protein 1

Plays a role in rod outer segment (ROS) morphogenesis. May play a role with PRPH2 in the maintenance of the structure of ROS curved disks. Plays a role in the organization of the ROS and maintenance of ROS disk diameter. Involved in the maintenance of the retina outer nuclear layer.

Retinitis pigmentosa 7 (RP7)

Photoreceptor inner segment membrane; Multi-pass membrane protein. Photoreceptor outer segment membrane; Multi-pass membrane protein.

PRPH2/ROM1 family

Retina photoreceptors (at protein level). In rim region of ROS disks.

ROM; RP7; ROSP1; TSPAN23; ROM1

This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa.