Amino acids 1-541 form the expressed segment for recombinant Human FTCD. This FTCD protein is expected to have a theoretical molecular weight of 60 kDa. This protein is generated in a yeast-based system. The FTCD gene fragment has been modified by fusing the C-terminal 6xHis tag, providing convenience in detecting and purifying the recombinant FTCD protein during the following stages.Human Formimidoyltransferase-Cyclodeaminase (FTCD) is a bifunctional enzyme involved in the histidine catabolic pathway. It consists of two domains: the formiminotransferase domain and the cyclodeaminase domain. In the formiminotransferase reaction, FTCD catalyzes the transfer of the formimino group from N-formimino-L-glutamate to tetrahydrofolate, producing formate and 5,10-methenyltetrahydrofolate. In the cyclodeaminase reaction, FTCD converts formiminoglutamate to formamide and ammonia. This enzyme plays a crucial role in maintaining histidine homeostasis and folate metabolism. Research on FTCD includes exploring its role in disorders related to histidine metabolism, understanding its impact on folate utilization, and investigating its potential implications in human health and diseases.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[24015],"class_list":["post-108904","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-ftcd","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n