Amino acids 1-375 constitute the expression domain of recombinant Human MEIS3. The expected molecular weight for the MEIS3 protein is calculated to be 48.6 kDa. This protein is generated in a e.coli-based system. The MEIS3 gene fragment has been modified by fusing the N-terminal 10xHis tag and C-terminal Myc tag, providing convenience in detecting and purifying the recombinant MEIS3 protein during the following stages.The human homeobox protein Meis3 (MEIS3) belongs to the TALE (Three-Amino Acid Loop Extension) superclass of homeodomain transcription factors. MEIS3 is involved in embryonic development, where it plays a crucial role in specifying cell fate and pattern formation. It participates in the development of various tissues and organs, including the brain, heart, and hematopoietic system. MEIS3 is known to interact with other transcription factors and co-factors to regulate gene expression, influencing processes such as cell proliferation, differentiation, and organogenesis. Additionally, MEIS3 has been implicated in certain cancers, highlighting its significance in both normal development and pathological conditions.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[9434],"class_list":["post-109198","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-meis3","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n