The expression region of this recombinant Human PNMA1 covers amino acids 1-353. The expected molecular weight for the PNMA1 protein is calculated to be 46.8 kDa. The PNMA1 protein was expressed in e.coli. The PNMA1 coding gene included the N-terminal 10xHis-B2M-JD tag and C-terminal Myc tag, which simplifies the detection and purification processes of the recombinant PNMA1 protein in following stages of expression and purification.Paraneoplastic antigen Ma1 (PNMA1) is a protein associated with paraneoplastic neurological disorders (PND), a group of rare conditions where the immune system mistakenly targets normal neural tissues in response to an underlying tumor, often affecting the nervous system. PNMA1 is expressed in the brain and is associated with onconeural antibodies found in patients with PND. Investigations into the molecular pathways involving PNMA1 contribute to the broader understanding of autoimmune reactions associated with cancer and may offer insights into novel treatment strategies for paraneoplastic neurological disorders.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[37328],"class_list":["post-109404","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-pnma1","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n