The region for expressing recombinant Human GABRB2 contains amino acids 26-244. The calculated molecular weight for this GABRB2 protein is 29.3 kDa. The GABRB2 protein was expressed in e.coli. The GABRB2 gene fragment has been modified by fusing the N-terminal 6xHis tag, providing convenience in detecting and purifying the recombinant GABRB2 protein during the following stages.The human Gamma-aminobutyric acid receptor subunit beta-2 (GABRB2) is a component of the GABAA receptor, a ligand-gated ion channel that plays a crucial role in inhibitory neurotransmission within the central nervous system. GABRB2 is involved in forming functional GABAergic receptors. Activation of these receptors by the neurotransmitter gamma-aminobutyric acid (GABA) leads to an influx of chloride ions, resulting in membrane hyperpolarization and neuronal inhibition. GABRB2’s presence in the GABAA receptor complex contributes to the regulation of neuronal excitability and is implicated in various neurological and psychiatric disorders, making it a target of interest in pharmacological research and drug development.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[36065],"class_list":["post-109466","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-gabrb2","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n