Transmembrane Ascorbate-Dependent Reductase Cyb561 (CYB561) Reagents

Transmembrane ascorbate-dependent reductase CYB561

Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce monodehydro-L-ascorbate radical in the lumen of secretory vesicles. It is therefore involved the regeneration and homeostasis within secretory vesicles of ascorbate which in turn provides reducing equivalents needed to support the activity of intravesicular enzymes.

Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Multi-pass membrane protein.

Expressed in many tissues, in particular the brain especially in the cortex and hippocampus.

CYB561; Transmembrane ascorbate-dependent reductase CYB561; Cytochrome b-561; Cytochrome b561