Dnaj Homolog Subfamily C Member 27 (DNAJC27) Reagents

DnaJ homolog subfamily C member 27

GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.

Nucleus.

Small GTPase superfamily, Rab family

Overexpressed in gastrointestinal cancers; expression correlates with later tumor-node-metastasis stages of colorectal cancers.

DJC27_HUMAN; DKFZp434N211; DnaJ (Hsp40) homolog, subfamily C, member 27; DnaJ homolog subfamily C member 27; DNAJC27; rab and DnaJ domain containing; Rab and DnaJ domain-containing protein; RABJS; Ras associated protein Rap1; RBJ