Large Ribosomal Subunit Protein Bl33M (MRPL33) Reagents

Large ribosomal subunit protein bL33m

Mitochondrion.

Bacterial ribosomal protein bL33 family

39S ribosomal protein L33; L33mt; mitochondrial; MRP-L33; mRpL33; RM33_HUMAN

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternatively spliced transcript variants encoding different isoforms have been described.