The expression region of this recombinant Human FOXL2 covers amino acids 1-376. The expected molecular weight for the FOXL2 protein is calculated to be 43.8 kDa. Expression of this FOXL2 protein is conducted in e.coli. The FOXL2 coding gene included the N-terminal 10xHis tag and C-terminal Myc tag, which simplifies the detection and purification processes of the recombinant FOXL2 protein in following stages of expression and purification.The human forkhead box protein L2 (FOXL2) is a transcription factor that plays a crucial role in various developmental processes, particularly in the development of ovarian tissues. FOXL2 is prominently expressed in ovarian granulosa cells, contributing to ovarian function and folliculogenesis. Mutations in the FOXL2 gene are associated with blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES), a genetic disorder characterized by eyelid malformations and ovarian dysfunction in affected females. Beyond its developmental role, FOXL2 is implicated in maintaining granulosa cell identity and suppressing male-specific gene expression in ovarian tissues. Understanding FOXL2’s functions is essential for unraveling the complexities of ovarian development and related genetic disorders.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[8459],"class_list":["post-108448","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-foxl2","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n