The region for expressing recombinant Human TLN1 contains amino acids 92-399. The theoretical molecular weight of the TLN1 protein is 62.8 kDa. This protein is generated in a e.coli-based system. The N-terminal GST tag was fused into the coding gene segment of TLN1, making it easier to detect and purify the TLN1 recombinant protein in the later stages of expression and purification.The human talin-1 (TLN1) is a cytoskeletal protein that plays a crucial role in cell adhesion by connecting integrin receptors to the actin cytoskeleton. TLN1 is essential for the formation and stabilization of focal adhesions, dynamic structures that mediate cell-extracellular matrix interactions. Through its interactions with integrins, TLN1 contributes to processes such as cell migration, spreading, and signaling. Additionally, TLN1 is involved in mechanotransduction, transmitting mechanical forces across the cell membrane. Dysregulation of TLN1 has been linked to various diseases, including cancer and cardiovascular disorders. Research on TLN1 explores its functions in cell adhesion, and signaling, and its implications in health and disease.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[39841],"class_list":["post-110113","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-tln1","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n