The region for expressing recombinant Human SERPINE1 contains amino acids 24-401. The theoretical molecular weight of the SERPINE1 protein is 46.7 kDa. This SERPINE1 protein is produced using e.coli expression system. The SERPINE1 coding gene included the N-terminal 6xHis tag, which simplifies the detection and purification processes of the recombinant SERPINE1 protein in following stages of expression and purification.Plasminogen activator inhibitor 1 (SERPINE1) is a member of the serine protease inhibitor (serpin) family and plays a crucial role in the regulation of fibrinolysis. SERPINE1 inhibits tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA), thus controlling the conversion of plasminogen to plasmin, a key enzyme in the dissolution of blood clots. Beyond its role in fibrinolysis, SERPINE1 is involved in various physiological and pathological processes, including tissue remodeling, inflammation, and cell migration. Dysregulation of SERPINE1 is implicated in conditions such as thrombosis, cardiovascular diseases, and cancer. Research on SERPINE1 explores its potential as a therapeutic target in diseases associated with altered fibrinolytic activity.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[48414],"class_list":["post-110200","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-serpine1","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n