Amino acids 16-498 constitute the expression domain of recombinant Human ANGPT1. This ANGPT1 protein is theoretically predicted to have a molecular weight of 59.9 kDa. The ANGPT1 protein was expressed in e.coli. Fusion of the N-terminal 6xHis tag into the ANGPT1 encoding gene fragment was conducted, allowing for easier detection and purification of the ANGPT1 protein in subsequent stages.Human angiopoietin-1 (ANGPT1) is a crucial signaling protein in angiogenesis, acting on endothelial cells to regulate blood vessel formation and stability. It binds to the Tie-2 receptor, promoting vascular maturation and integrity. In cardiovascular research, ANGPT1 is essential for vascular development, and its dysregulation is implicated in vascular diseases. In regenerative medicine, ANGPT1 holds the potential for promoting tissue repair through angiogenesis. Additionally, ANGPT1 plays a role in cancer biology, influencing tumor angiogenesis. Investigating ANGPT1 provides insights into vascular biology, cardiovascular diseases, tissue regeneration, and cancer progression, offering avenues for therapeutic interventions in conditions related to angiogenesis and vascular homeostasis.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[49633],"class_list":["post-111569","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-angpt1","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n