The expression region of this recombinant Human DKK2 covers amino acids 34-259. This DKK2 protein is theoretically predicted to have a molecular weight of 41 kDa. This DKK2 recombinant protein is manufactured in e.coli. The N-terminal 6xHis-SUMO tag was fused into the coding gene segment of DKK2, making it easier to detect and purify the DKK2 recombinant protein in the later stages of expression and purification.Human dickkopf-related protein 2 (DKK2) is a member of the Dickkopf family of proteins, which are involved in the regulation of the Wnt signaling pathway. The Wnt signaling pathway plays a critical role in embryonic development, tissue homeostasis, and cell differentiation. DKK2 acts as an antagonist of Wnt signaling by binding to the LRP5\/6 co-receptors, preventing their interaction with Wnt ligands. By inhibiting Wnt signaling, DKK2 contributes to the regulation of cell fate decisions and tissue development. Dysregulation of DKK2 has been implicated in various diseases, including cancer, where altered Wnt signaling is often observed. Studying DKK2 provides insights into the intricate regulatory mechanisms of Wnt signaling and its implications in health and disease.<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[168834,18],"product_tag":[49170],"class_list":["post-111704","product","type-product","status-publish","product_cat-proteins","product_cat-recombinant-proteins","product_tag-dkk2","first","instock","shipping-taxable","product-type-simple"],"acf":[],"yoast_head":"\n