Rabbit anti-Human HRH3 Monoclonal Antibody

The antibody against HRH3 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human HRH3 (Q9Y5N1) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ELISA.

ADA-16192A

Number

Cat.No	ADA-16192A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	HRH3
Target Synonyms	HH3R; GPCR97; HRH3	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat brain, Mouse brain, Mouse spleen, Mouse testis, Raji, Rat spleen, Rat testis, SH-SY5Y, U-251MG	Application	ELISA, WB, IP

Cat.No

ADA-16192A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

HRH3

Target Synonyms

HH3R; GPCR97; HRH3

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat brain, Mouse brain, Mouse spleen, Mouse testis, Raji, Rat spleen, Rat testis, SH-SY5Y, U-251MG

Application

ELISA, WB, IP

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HRH3 (Q9Y5N1).	Target Species	Human
Immunogen Sequence	MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRW	Uniprot ID	Q9Y5N1

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HRH3 (Q9Y5N1).

Target Species

Human

Immunogen Sequence

MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRW

Uniprot ID

Q9Y5N1

Background Information

Uniprot Id

Q9Y5N1
Target Species

Human
Target Name

HRH3
Target Full Name

Histamine H3 receptor
Target Function

The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

G-protein coupled receptor 1 family
Target Tissue Specificity

Expressed predominantly in the CNS, with the greatest expression in the thalamus and caudate nucleus. The various isoforms are mainly coexpressed in brain, but their relative expression level varies in a region-specific manner. Isoform 3 and isoform 7 are
Target Synonyms

HRH3; GPCR97; Histamine H3 receptor; H3R; HH3R; G-protein coupled receptor 97
Target Background

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.

Rabbit anti-Human HRH3 Monoclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human HRH3 Monoclonal Antibody Now

Related Products