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| Cat.No | ACP00251 | Target Name | SUN3 |
|---|---|---|---|
| Target Synonyms | Sad1/unc-84 domain-containing protein 1 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 65-357aa |
| Mol Weight | 34.8 kDa | Protein Length | Partial |
| Purity | Greater than 95% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8TAQ9 |
|---|
Uniprot Id
Q8TAQ9
Target Species
Human
Target Name
SUN3
Target Full Name
SUN domain-containing protein 3
Target Function
As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenenis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.
Target Subcellular Location
Membrane; Single-pass membrane protein. Nucleus envelope. Nucleus inner membrane.
Target Research Area
Cell Biology
Target Synonyms
SUN3; SUNC1; SUN domain-containing protein 3; Sad1/unc-84 domain-containing protein 1
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