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| Cat.No | ACP00724 | Target Name | SOX1 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 1-391aa | Mol Weight | 46.5 |
| Protein Length | Full length | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O00570 |
|---|
Uniprot Id
O00570
Target Species
Human
Target Name
SOX1
Target Full Name
Transcription factor SOX-1
Target Function
Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Mainly expressed in the developing central nervous system.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
Sex determining region Y box 1; sox1; SOX1_HUMAN; SRY; SRY box containing gene 1; SRY related HMG box gene 1; Transcription factor Sox-1
Target Background
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.
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