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Recombinant Human Zinc finger protein ZIC 2 (ZIC2), Truncated

ACP01894

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Specifications

Cat.No	ACP01894	Target Name	ZIC2
Target Synonyms	Zinc finger protein of the cerebellum 2	Form	Liquid or Lyophilized powder
Expression System	E.coli	Expression Range	100-415aa
Mol Weight	41.6 kDa	Protein Length	Partial
Purity	Greater than 85% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O95409

Background Information

Uniprot Id

O95409
Target Species

Human
Target Name

ZIC2
Target Full Name

Zinc finger protein ZIC 2
Target Function

Acts as a transcriptional activator or repressor. Plays important roles in the early stage of organogenesis of the CNS. Activates the transcription of the serotonin transporter SERT in uncrossed ipsilateral retinal ganglion cells (iRGCs) to refine eye-specific projections in primary visual targets. Its transcriptional activity is repressed by MDFIC. Involved in the formation of the ipsilateral retinal projection at the optic chiasm midline. Drives the expression of EPHB1 on ipsilaterally projecting growth cones. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'. Associates to the basal SERT promoter region from ventrotemporal retinal segments of retinal embryos
Target Involvement

Holoprosencephaly 5 (HPE5)
Target Subcellular Location

Nucleus. Cytoplasm.
Target Protein Families

GLI C2H2-type zinc-finger protein family
Target Research Area

Epigenetics and Nuclear Signaling
Target Synonyms

HPE 5; HPE5; Odd paired homolog Drosophila; Zic 2; Zic family member 2 (odd paired Drosophila homolog); Zic family member 2; ZIC2; ZIC2_HUMAN; Zinc finger protein of the cerebellum 2; Zinc finger protein ZIC 2; Zinc finger protein Zic2

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Recombinant Human Zinc finger protein ZIC 2 (ZIC2), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Zinc finger protein ZIC 2 (ZIC2), Truncated Now

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