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| Cat.No | ACP02147 | Target Name | SRD5A2 |
|---|---|---|---|
| Target Synonyms | Pro-NRG3 | Form | Liquid or Lyophilized powder |
| Expression System | in vitro E.coli expression system | Expression Range | 1-254aa |
| Mol Weight | 29.4 | Protein Length | Full length |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P31213 |
|---|
Uniprot Id
P31213
Target Species
Human
Target Name
SRD5A2
Target Full Name
3-oxo-5-alpha-steroid 4-dehydrogenase 2
Target Function
Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Target Involvement
Pseudovaginal perineoscrotal hypospadias (PPSH)
Target Subcellular Location
Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
Steroid 5-alpha reductase family
Target Tissue Specificity
Expressed in high levels in the prostate and many other androgen-sensitive tissues.
Target Research Area
Cell Biology
Target Synonyms
SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2; 5 alpha-SR2; SR type 2; Steroid 5-alpha-reductase 2; S5AR 2; Type II 5-alpha reductase
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