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Recombinant Human Histone deacetylase 11 (HDAC11)

ACP03387

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Specifications

Cat.No	ACP03387	Target Name	HDAC11
Target Synonyms	FLJ22237; HD 11; HD11; HDA11_HUMAN; HDAC 11; HDAC11; Histone deacetylase 11	Form	Liquid or Lyophilized powder
Expression System	E.coli	Expression Range	1-347aa
Mol Weight	66.2kDa	Protein Length	Full length
Purity	Greater than 90% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96DB2

Background Information

Uniprot Id

Q96DB2
Target Species

Human
Target Name

HDAC11
Target Full Name

Histone deacetylase 11
Target Function

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Target Subcellular Location

Nucleus. Note=Predominantly nuclear.
Target Protein Families

Histone deacetylase family
Target Tissue Specificity

Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis.
Target Research Area

Epigenetics and Nuclear Signaling
Target Synonyms

FLJ22237; HD 11; HD11; HDA11_HUMAN; HDAC 11; HDAC11; Histone deacetylase 11
Target Background

This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.

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Recombinant Human Histone deacetylase 11 (HDAC11)

Specifications

Immunogen Information

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