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Enhance your research with our premium Recombinant Human GDI2 protein, also known as Rab GDP dissociation inhibitor beta (Rab GDI beta). GDI2 plays a critical role in the regulation of vesicular transport by modulating the GDP/GTP exchange reaction of Rab proteins, thereby controlling their membrane cycling between the cytosol and membranes. Its importance in cellular trafficking and membrane dynamics makes GDI2 an essential component for various research applications. Our Recombinant Human GDI2 protein is expressed in a yeast system, ensuring proper folding and post-translational modifications. The full-length protein sequence (1-445aa) is N-terminal 6xHis-tagged for efficient purification while preserving native structure and function. With a purity greater than 90% as determined by SDS-PAGE, our GDI2 protein guarantees consistent and reliable results in your experiments. Available in both liquid and lyophilized powder forms, our Recombinant Human GDI2 protein is ready to support your research goals.
Enhance your research with our premium Recombinant Human GDI2 protein, also known as Rab GDP dissociation inhibitor beta (Rab GDI beta). GDI2 plays a critical role in the regulation of vesicular transport by modulating the GDP/GTP exchange reaction of Rab proteins, thereby controlling their membrane cycling between the cytosol and membranes. Its importance in cellular trafficking and membrane dynamics makes GDI2 an essential component for various research applications.
Our Recombinant Human GDI2 protein is expressed in a yeast system, ensuring proper folding and post-translational modifications. The full-length protein sequence (1-445aa) is N-terminal 6xHis-tagged for efficient purification while preserving native structure and function. With a purity greater than 90% as determined by SDS-PAGE, our GDI2 protein guarantees consistent and reliable results in your experiments. Available in both liquid and lyophilized powder forms, our Recombinant Human GDI2 protein is ready to support your research goals.
| Cat.No | ACP03887 | Target Name | GDI2 |
|---|---|---|---|
| Target Synonyms | GDI-2; GDI2; GDIB_HUMAN; GDP dissociation inhibitor 2; Guanosine diphosphate dissociation inhibitor 2; Rab GDI beta; Rab GDP dissociation inhibitor beta; RABGDIB | Form | Liquid or Lyophilized powder |
| Expression System | Yeast | Expression Range | 1-445aa |
| Mol Weight | 52.7 kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P50395 |
|---|
Uniprot Id
P50395
Target Species
Human
Target Name
GDI2
Target Full Name
Rab GDP dissociation inhibitor beta
Target Function
Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
Target Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein.
Target Protein Families
Rab GDI family
Target Tissue Specificity
Ubiquitous.
Target Research Area
Signal Transduction
Target Synonyms
GDI-2; GDI2; GDIB_HUMAN; GDP dissociation inhibitor 2; Guanosine diphosphate dissociation inhibitor 2; Rab GDI beta; Rab GDP dissociation inhibitor beta; RABGDIB
Target Background
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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