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| Cat.No | ACP06083 | Target Name | RHBDF2 |
|---|---|---|---|
| Target Synonyms | RHBDF2; IRHOM2; RHBDL5; RHBDL6; Inactive rhomboid protein 2; iRhom2; Rhomboid 5 homolog 2; Rhomboid family member 2; Rhomboid veinlet-like protein 5; Rhomboid veinlet-like protein 6 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6PJF5 |
|---|
Uniprot Id
Q6PJF5
Target Species
Human
Target Name
RHBDF2
Target Full Name
Inactive rhomboid protein 2
Target Function
Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.
Target Involvement
Tylosis with esophageal cancer (TOC)
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane.
Target Protein Families
Peptidase S54 family
Target Tissue Specificity
Found in the epidermis and esophageal epithelium.
Target Synonyms
RHBDF2; IRHOM2; RHBDL5; RHBDL6; Inactive rhomboid protein 2; iRhom2; Rhomboid 5 homolog 2; Rhomboid family member 2; Rhomboid veinlet-like protein 5; Rhomboid veinlet-like protein 6
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