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| Cat.No | ACP07782 | Target Name | SPTSSA |
|---|---|---|---|
| Target Synonyms | SPTSSA; C14orf147; SSSPTA; Serine palmitoyltransferase small subunit A; Small subunit of serine palmitoyltransferase A; ssSPTa | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q969W0 |
|---|
Uniprot Id
Q969W0
Target Species
Human
Target Name
SPTSSA
Target Full Name
Serine palmitoyltransferase small subunit A
Target Function
Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. Plays a role in MBOAT7 location to mitochondria-associated membranes (MAMs), may me involved in fatty acid remodeling phosphatidylinositol (PI).
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
SPTSS family, SPTSSA subfamily
Target Synonyms
SPTSSA; C14orf147; SSSPTA; Serine palmitoyltransferase small subunit A; Small subunit of serine palmitoyltransferase A; ssSPTa
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