Recombinant Human Probable ATP-dependent RNA helicase DDX41 (DDX41)

Uniprot Id

Q9UJV9

Target Species

Human

Target Name

DDX41

Target Full Name

Probable ATP-dependent RNA helicase DDX41

Target Function

Probable ATP-dependent RNA helicase. Is required during post-transcriptional gene expression. May be involved in pre-mRNA splicing.

Target Involvement

Myeloproliferative/lymphoproliferative neoplasms, familial (MPLPF)

Target Subcellular Location

Nucleus.

Target Protein Families

DEAD box helicase family, DDX41 subfamily

Target Synonyms

2900024F02Rik ; AA958953; ABS; AI324246; Ddx41; DDX41_HUMAN; DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; DEAD box protein 41; DEAD box protein abstrakt; DEAD box protein abstrakt homolog; EC 3.6.1.-; fb92e02; MGC55896; MGC8828; Probable ATP-dependent RNA helicase DDX41; Putative RNA helicase; wu:fb92e02 ; zgc:55896

Target Background

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD box protein family and interacts with several spliceosomal proteins. In addition, the encoded protein may recognize the bacterial second messengers cyclic di-GMP and cyclic di-AMP, resulting in the induction of genes involved in the innate immune response.