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| Cat.No | ACP10202 | Target Name | HECW2 |
|---|---|---|---|
| Target Synonyms | C2 and WW domain-containing protein 2; E3 ubiquitin protein ligase HECW2; E3 ubiquitin-protein ligase HECW2; HECT; HECT | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9P2P5 |
|---|
Uniprot Id
Q9P2P5
Target Species
Human
Target Name
HECW2
Target Full Name
E3 ubiquitin-protein ligase HECW2
Target Function
E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. Involved in the regulation of mitotic metaphase/anaphase transition.
Target Involvement
Neurodevelopmental disorder with hypotonia, seizures, and absent language (NDHSAL)
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, spindle.
Target Tissue Specificity
Predominantly expressed in adult brain, lung and heart.
Target Synonyms
C2 and WW domain-containing protein 2; E3 ubiquitin protein ligase HECW2; E3 ubiquitin-protein ligase HECW2; HECT; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2; Hecw2; HECW2_HUMAN; KIAA130; KIAA1301; NEDD4 like E3 ubiquitin protein ligase 2; NEDD4 Related E3 Ubiquitin Ligase; NEDD4-like E3 ubiquitin-protein ligase 2
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