Recombinant Human Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A), Truncated

Cat.No	ACP10582	Target Name	BAZ1A
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP10582

Target Name

BAZ1A

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q9NRL2

Background Information

Uniprot Id

Q9NRL2
Target Species

Human
Target Name

BAZ1A
Target Full Name

Bromodomain adjacent to zinc finger domain protein 1A
Target Function

Regulatory subunit of the ATP-dependent ACF-1 and ACF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and slide edge- and center-positioned histone octamers away from their original location on the DNA template to facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template in an ATP-dependent manner. The ACF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the ACF-5 ISWI chromatin remodeling complex. Has a role in sensing the length of DNA which flank nucleosomes, which modulates the nucleosome spacing activity of the ACF-5 ISWI chromatin remodeling complex. Involved in DNA replication and together with SMARCA5/SNF2H is required for replication of pericentric heterochromatin in S-phase. May have a role in nuclear receptor-mediated transcription repression.
Target Subcellular Location

Nucleus. Note=May target the CHRAC complex to heterochromatin.
Target Protein Families

WAL family
Target Tissue Specificity

Highly expressed in testis and at low or undetectable levels in other tissues analyzed.
Target Synonyms

Acf1; ACF1; drosophila; homolog of; ATP dependent chromatin remodelling protein; ATP utilizing chromatin assembly and remodeling factor 1; ATP-dependent chromatin-remodeling protein; ATP-utilizing chromatin assembly and remodeling factor 1; B930060C03; Baz1a; BAZ1A_HUMAN; BC065123; Bromodomain adjacent to zinc finger domain 1A; Bromodomain adjacent to zinc finger domain protein 1A; cbp146; CHRAC subunit ACF1; DKFZp586E0518; FLJ14383; Gtl5; hACF1; hWALp1; WALp1; WCRF180; Williams syndrome transcription factor related chromatin remodeling factor 180; Williams syndrome transcription factor-related chromatin-remodeling factor 180
Target Background

The BAZ1A gene encodes the accessory subunit of the ATP-dependent chromatin assembly factor (ACF), a member of the ISWI ('imitation switch') family of chromatin remodeling complexes (summarized by Racki et al., 2009 [PubMed 20033039]).

Recombinant Human Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A), Truncated Now

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