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| Cat.No | ACP11660 | Target Name | HESX1 |
|---|---|---|---|
| Target Synonyms | HESX1; HANF; Homeobox expressed in ES cells 1; Homeobox protein ANF; hAnf | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-185 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UBX0 |
|---|
Uniprot Id
Q9UBX0
Target Species
Human
Target Name
HESX1
Target Full Name
Homeobox expressed in ES cells 1
Target Function
Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and pituitary gland. Possible transcriptional repressor. Binds to the palindromic PIII sequence, 5'-AGCTTGAGTCTAATTGAATTAACTGTAC-3'. HESX1 and PROP1 bind as heterodimers on this palindromic site, and, in vitro, HESX1 can antagonize PROP1 activation.
Target Involvement
Septooptic dysplasia (SOD); Growth hormone deficiency with pituitary anomalies (GHDPA); Pituitary hormone deficiency, combined, 5 (CPHD5)
Target Subcellular Location
Nucleus.
Target Protein Families
ANF homeobox family
Target Synonyms
HESX1; HANF; Homeobox expressed in ES cells 1; Homeobox protein ANF; hAnf
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