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| Cat.No | ACP11707 | Target Name | ETAA1 |
|---|---|---|---|
| Target Synonyms | Etaa1; ETAA1_HUMAN; ETAA16; Ewing''s tumor-associated antigen 1; Ewing''s tumor-associated antigen 16 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NY74 |
|---|
Uniprot Id
Q9NY74
Target Species
Human
Target Name
ETAA1
Target Full Name
Ewing's tumor-associated antigen 1
Target Function
Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity. Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1. Probably only regulates a subset of ATR targets.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.
Target Synonyms
Etaa1; ETAA1_HUMAN; ETAA16; Ewing''s tumor-associated antigen 1; Ewing''s tumor-associated antigen 16
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