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| Cat.No | ACP12203 | Target Name | HAUS8 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 2-410 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BT25 |
|---|
Uniprot Id
Q9BT25
Target Species
Human
Target Name
HAUS8
Target Full Name
HAUS augmin-like complex subunit 8
Target Function
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.
Target Protein Families
HAUS8 family
Target Synonyms
DGT4; HAUS augmin like complex subunit 8; HAUS augmin-like complex subunit 8; HAUS8; HAUS8_HUMAN; Hec1 interacting and centrosome associated 1; HEC1/NDC80 interacting centrosome associated protein 1; HEC1/NDC80-interacting centrosome-associated protein 1; HICE 1; HICE1; MGC20533; NY SAR 48; NY-SAR-48; Sarcoma antigen NY SAR 48; Sarcoma antigen NY-SAR-48
Target Background
HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare, ' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).
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