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| Cat.No | ACP12331 | Target Name | BBC3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-193 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BXH1 |
|---|
Uniprot Id
Q9BXH1
Target Species
Human
Target Name
BBC3
Target Full Name
Bcl-2-binding component 3, isoforms 1/2
Target Function
Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
Target Subcellular Location
Mitochondrion. Note=Localized to the mitochondria in order to induce cytochrome c release.
Target Protein Families
Bcl-2 family
Target Tissue Specificity
Ubiquitously expressed.
Target Synonyms
BBC 3; Bbc3; BBC3_HUMAN; BCL 2 binding component 3; Bcl-2-binding component 3; BCL2 binding component 3; JFY 1; JFY-1; JFY1; p53 up regulated modulator of apoptosis; p53 up-regulated modulator of apoptosis; p53 Upregulated Modulator of Apoptosis; PUMA alpha; PUMA/JFY1
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