Recombinant Human GAS2-like protein 1 (GAS2L1)

Uniprot Id

Q99501

Target Species

Human

Target Name

GAS2L1

Target Full Name

GAS2-like protein 1

Target Function

Involved in the cross-linking of microtubules and microfilaments. Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers.

Target Subcellular Location

Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber.

Target Protein Families

GAS2 family

Target Synonyms

GA2L1_HUMAN; GAR 22; GAR22; GAS2 like protein 1; GAS2 related protein on chromosome 22 ; GAS2-like protein 1; GAS2-related protein on chromosome 22; GAS2L1; Growth arrest specific 2 like 1; Growth arrest specific protein 2 like 1; Growth arrest-specific protein 2-like 1; MGC17243

Target Background

This gene encodes a member of the growth arrest-specific 2 protein family. This protein binds components of the cytoskeleton and may be involved in mediating interactions between microtubules and microfilaments. This protein localizes to the proximal end of mature centrioles and links centrosomes to both microtubules and actin. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 9.