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Recombinant Human Leucine-rich repeat-containing protein 7 (LRRC7), Truncated

ACP12873

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP12873 Target NameLRRC7
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ96NW7
Background Information
  • Uniprot Id

    Q96NW7

  • Target Species

    Human

  • Target Name

    LRRC7

  • Target Full Name

    Leucine-rich repeat-containing protein 7

  • Target Function

    Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression.

  • Target Subcellular Location

    Cytoplasm. Cell junction, synapse, postsynaptic density.

  • Target Protein Families

    LAP (LRR and PDZ) protein family

  • Target Tissue Specificity

    Brain-specific. Isoform 3 is ubiquitously expressed.

  • Target Synonyms

    Densin 180; Densin; Densin-180; densin180; DKFZp686I1147; KIAA1365; Lamin associated polypeptide 1; LAP 1; Leucine rich repeat containing 7; Leucine rich repeat containing protein 7; Leucine-rich repeat-containing protein 7; Lrrc 7 ; LRRC7; LRRC7_HUMAN; MGC144918; OTTHUMP00000065336; OTTHUMP00000065337; OTTHUMP00000065338; Protein Lap 1; Protein lap1

  • Target Background

    Predicted to be involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; positive regulation of neuron projection development; and receptor clustering. Located in several cellular components, including centrosome; cytosol; and nucleoplasm.

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