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Recombinant Human Multivesicular body subunit 12A (FAM125A)

ACP13509

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Specifications

Cat.No	ACP13509	Target Name	MVB12A
Target Synonyms	MVB12A; CFBP; FAM125A; Multivesicular body subunit 12A; CIN85/CD2AP family-binding protein; ESCRT-I complex subunit MVB12A; Protein FAM125A	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-273
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96EY5

Background Information

Uniprot Id

Q96EY5
Target Species

Human
Target Name

MVB12A
Target Full Name

Multivesicular body subunit 12A
Target Function

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor.
Target Subcellular Location

Cytoplasm. Nucleus. Endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Late endosome membrane; Peripheral membrane protein. Note=Colocalizes with F-actin. Some fraction may be nuclear.
Target Protein Families

MVB12 family
Target Tissue Specificity

Ubiquitously expressed except in skeletal muscle.
Target Synonyms

MVB12A; CFBP; FAM125A; Multivesicular body subunit 12A; CIN85/CD2AP family-binding protein; ESCRT-I complex subunit MVB12A; Protein FAM125A
Target Background

Enables lipid binding activity and ubiquitin binding activity. Involved in regulation of epidermal growth factor receptor signaling pathway; viral budding; and virus maturation. Located in several cellular components, including Golgi apparatus; centrosome; and nucleoplasm. Part of ESCRT I complex.

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Recombinant Human Multivesicular body subunit 12A (FAM125A)

Specifications

Immunogen Information

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