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| Cat.No | ACP13792 | Target Name | C5orf30 |
|---|---|---|---|
| Target Synonyms | C5orf30; CE030_HUMAN; chromosome 5 open reading frame 30; D1Ertd622e; FLJ25291; UNC119-binding protein C5orf30 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-206 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96GV9 |
|---|
Uniprot Id
Q96GV9
Target Species
Human
Target Name
MACIR
Target Full Name
Macrophage immunometabolism regulator
Target Function
Regulates the macrophage function, by enhancing the resolution of inflammation and wound repair functions mediated by M2 macrophages. The regulation of macrophage function is, due at least in part, to its ability to inhibit glycolysis. May also play a role in trafficking of proteins via its interaction with UNC119 and UNC119B cargo adapters: may help the release of UNC119 and UNC119B cargo or the recycling of UNC119 and UNC119B. May play a role in ciliary membrane localization via its interaction with UNC119B and protein transport into photoreceptor cells.
Target Subcellular Location
Cytoplasm. Cell projection, cilium.
Target Protein Families
UNC119-binding protein family
Target Tissue Specificity
High expression in normal macrophages, monocytes, and cultured rheumatoid arthritis synovial fibroblasts (RASFs), with lower expression in B- and T-cells, and little to no expression in other tissues and cell lines.
Target Synonyms
C5orf30; CE030_HUMAN; chromosome 5 open reading frame 30; D1Ertd622e; FLJ25291; UNC119-binding protein C5orf30
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